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Focal Therapy Finder

Focal therapy doctors in the United States

149 doctors at 135 practices in 35 states are listed for focal therapy of prostate cancer with irreversible electroporation (IRE, known as NanoKnife). Choose a state, or search by ZIP code.

By state

Approval and coverage

FDA 510(k) clearance
The FDA cleared the NanoKnife System for prostate tissue ablation in December 2024, based on the PRESERVE trial in intermediate-risk prostate cancer.
Billing code and Medicare
A dedicated Category I CPT code for prostate IRE took effect on 1 January 2026, and Medicare coverage criteria (Palmetto GBA LCD) apply from July 2026. Humana Medicare Advantage follows those criteria from October 2026. Ask your doctor and insurer what applies to you.

This page last changed 2026-10-22.